For beginner friendliness it is best to get mildew resistant varieties so you won't have to spray. There are a good number on the market these days.
Suggested varieties for red:
Regent (mid early) - Makes a very good wine, think Corbieres or Cote du Roussillon. Big berries excellent for eating too but they do have a large pip. They may also take longer to find their feet before cropping but well worth it.
Rondo (early ripening and early bearing) - nice clean berries with good ripeness. Makes a good wine but with a distinctive flavour. Distinctive does not mean bad.
Cabernet Cortis (mid early) - probably the most promising red wine variety for the british climate. Wine described as a Cabernet Sauvignon/ Merlot style.
Suggested varieties for white:
Phoenix (mid early) - Excellent all rounder for wine and eating. Very sweet.
Zalagyongye (mid early) - Lovely large berries on long bunches. Great for eating or wine.
Solaris (very early, strong grower) - Considered by some as the most promising UK white wine variety because of its early ripening and very high sugar levels (sufficient to make 12% alcohol on its own! hic)
All these are easy to grow, though none are seedless, as well as being disease free. There are others but these are my recommendations.
For more inspiration have a look at the holder of the National Collection of Grape Vines website.
http://www.sunnybankvines.co.uk/Planting then side by side is fine (at least six feet apart though). They are self fertile so no problem if you want to grow them away from one another.